Podcast
0.25 CME Credit
The Dual Advantage: Improving Alzheimer Care with Combination Therapy - Frankly Speaking Ep 399Guest: Jillian Joseph, MPAS, PA-C
Music Credit: Matthew Bugos
In this episode, we look at a new study showing increased probability of survival for patients with Alzheimer disease (AD) who take donepezil and memantine together. We review current treatments for AD and address common hesitations in prescribing dual pharmacotherapy, providing vital insights for primary care clinicians.
Episode references and resource links:
- Yaghmaei, E., Lu, H., Ehwerhemuepha, L. et al. Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimer’s disease patients.Commun Med 4, 99 (2024). https://doi.org/10.1038/s43856-024-00527-6
- Guo J, Wang Z, Liu R, Huang Y, Zhang N, Zhang R. Memantine, Donepezil, or Combination Therapy-What is the best therapy for Alzheimer's Disease? A Network Meta-Analysis. Brain Behav. 2020 Nov;10(11):e01831. doi: 10.1002/brb3.1831. Epub 2020 Sep 10. PMID: 32914577; PMCID: PMC7667299.
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CME/CE Information
0.25 AMA PRA Category 1 Credits™
Release Date: 9/23/2024
Expiration Date: 9/23/2026
Learning Objectives
- Review the currently available medical therapies for Alzheimer disease (AD)
- Discuss the benefits of combination drug therapy for AD
Faculty
Frank J. Domino, MD
Professor, Family Medicine and Community Health,
University of Massachusetts Medical School, Worcester, MA
Jillian Joseph, MPAS, PA-C
Assistant Professor, Department of PA Studies, Massachusetts College of Pharmacy, Boston, MA
Clinical Instructor, Department of Family Medicine & Community Health, University of Massachusetts Medical School, Worcester, MA
Disclosures
Frank J. Domino, MD: Has disclosed no relevant financial relationships.
Jillian Joseph, MPAS, PA-C: Has disclosed no relevant financial relationships.
Non-faculty contributors involved in the planning, development, editing, and review of the content have disclosed no relevant financial relationships.
CME/CE Information
AMA PRA Category 1 Credits™
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