Podcast
0.25 CME Credit
Addressing Penicillin Allergies in Primary Care - Frankly Speaking Ep 356Guest: Robert A. Baldor MD, FAAFP
Music Credit: Richard Onorato
Patient-reported penicillin allergies are common; however, more than 95% of such patients have negative penicillin allergy testing and will tolerate subsequent antibiotic use. Currently, disproving a penicillin allergy includes negative skin testing followed by an oral challenge, which is considered the gold standard to remove the penicillin allergy label, as skin testing alone lacks 100% negative predictive value. Recent reports have suggested that low-risk individuals can be assessed with a direct oral challenge, but the safety and efficacy of such an approach has not been rigorously studied. Listen in as expert faculty discuss a recent randomized controlled trial that validates such an approach.
Episode references and resource links:
- Trubiano JA, Vogrin S, Chua KYL et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Internal Med. Published March 16, 2020. doi:10.1001/jamainternmed.2020.0403
- JAMA Intern Med. doi:10.1001/jamainternmed.2023.2986
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CME/CE Information
0.25 AMA PRA Category 1 Credits
Release Date: 11/27/2023
Expiration Date: 11/27/2025
Topics
Learning Objectives
- Describe the epidemiology of penicillin allergies and their impact on care
- Explain how to address penicillin allergies in the primary care setting
Faculty
Frank J. Domino, MD
Professor, Family Medicine and Community Health,
University of Massachusetts Medical School, Worcester, MA
Robert A. Baldor, MD, FAAFP
Professor and Chairman, Dept of Family Medicine
UMass Medical School/Baystate
Disclosures
Frank J. Domino, MD: Has disclosed no relevant financial relationships.
Robert A. Baldor MD, FAAFP: Has disclosed no relevant financial relationships.
Non-faculty contributors involved in the planning, development, editing, and review of the content have disclosed no relevant financial relationships.
CME/CE Information
AMA PRA Category 1 Credits
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